The Hindukush Range has some of the most majestic and least explored mountains in the Himalayas. The giants of the Hindukush can be seen from flights between Europe and Pakistan. Because of the proximity to the Afghan border very few American expeditions have ventured into this area. While the Americans stay away, the French bag first ascents every year.
You can take a flight from Islamabad to Peshawer, and then a flight from Peshawer to Chitral. Chitral can also be reached by crossing the Shandur Pass from Ghizar (nearest airport would be Gilgit). From Chitral daily vans leave for villages close to the three major peaks: Tirich Mir, Buni Zom, and Noshaq.